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  • 2024-07-10

    Transmittance Contrast-induced Photocurrent: A General Strategy for Self-powered Photodetectors Based on MXene Electrodes
    The regulation of carrier generation and transport by Schottky junctions enables effective optoelectronic conversion in optoelectronic devices. A simple and general strategy to spontaneously generate photocurrent is of great significance for self-powered photodetectors but is still being pursued. He
  • 2024-07-10

    Orientation-engineered 2D Electronics on Van Der Waals Dielectrics
    van der Waals (vdWs) dielectrics are widely used in nanoelectronics to preserve the intrinsic properties of two-dimensional (2D) semiconductors. However, achieving aligned growth of 2D semiconductors and their direct utilization on original vdWs epitaxial dielectrics
  • 2024-07-10

    Ultra-high Capacity And Stable Dual-ion Batteries with Fast Kinetics Enabled by HOF Supermolecules Derived 3D Nitrogen-Oxygen Co-doped Nanocarbon Anodes
    The low capacity, poor cycling life, and rapid self-discharge hinder the development of carbonaceous dual-ion batteries (DIBs). Conventional preparations of element doping amorphous carbons are cumbersome, complex, and difficult to control the doping element, content, and size.
  • 2024-07-10

    Titanium Nitride Induced Wide Temperature Range Self-lubricating Silicon Nitride Ceramics with Low Wear And Stable Low Friction Coefficient
    Silicon nitride (Si3N4) with excellent mechanical properties and chemical stability, has been widely used in many fields. However, wear failure is often the cause of the short life of Si3N4 devices at high temperatures, thereby the wear resistance of Si3N4 ceramics still needs to be further improved.
  • 2024-07-10

    什么是靶向蛋白降解(PROTAC)
    PROTAC (Proteolysis Targeting Chimeras,蛋白降解靶向联合体)的概念是在2001年由Crews等人提出,能够利用机体内天然存在的蛋白清理系统,降低蛋白水平而非抑制蛋白的功能。PROTAC技术经过20年的不断完善和发展,俨然成为目前新药研发领域最火热的技术之一,受到科研院所、药企和投资机构的青睐。PROTAC(Proteolysis TargetingChimeras)是一种治疗策略,旨在通过促使特定蛋白质在细胞内被泛素化和降解来调节蛋白质水平和功能。这种方法利用异双功能分子,包含一个与目标蛋白质结合的部分和一个与E3连接酶结合的部分。
  • 2024-07-10

    Sustained Delivery of Gemcitabine Via in Situ Injectable Mussel-inspired Hydrogels for The Local Therapy of Pancreatic Cancerc
    The issue of pervasively enhanced drug resistance of pancreatic cancer is fundamental to a better understanding of gemcitabine-based chemotherapy. Currently available treatment plans involving injectable therapeutics are mainly engineered to improve the performance and broaden their applications
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